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Glycine
Thermoregulation aid
Overview
A simple amino acid that promotes peripheral vasodilation, helping lower core body temperature for sleep onset.
How it works
Glycine is an inhibitory neurotransmitter in its own right. It also promotes peripheral blood flow, which shunts heat to the skin and lowers core temperature.
Benefits
Sleep quality: subjective improvement in multiple small trials.
B
Dosage
3 g before bed
Safety Profile
Research Summary
Safe, cheap, and backed by several small Japanese trials showing improved subjective sleep quality and next-day alertness.
Sources
Last updated: 2026-04-10
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Medical Disclaimer
This is a research summary, not medical advice. Body Signals is an independent research digest — it summarises published research for informational purposes and is not a healthcare provider. Supplements like melatonin, valerian, and magnesium can interact with prescription medications — check with your doctor or pharmacist before starting any supplement. Chronic insomnia may indicate an underlying condition (sleep apnoea, thyroid dysfunction, depression) and warrants a medical evaluation.
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